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| Date | Event |
| 1492 | Columbus settles in New World |
| 1504 | French sailors discover Grand Banks |
| 1585 | First British settlment at Roanoke, Virginia founded by Sir Walter Raleigh
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| 1603 | James VI of Scotland becomes James I of England |
| 1606 | Land clearances begin in Scotland – lowlanders moved to Ulster, Ireland |
| 1607 | Foundation of Jamestown |
| 1640s | Scots emigrated to New World as religious refugees |
| 1650 | Battle of Dunbar – Cromwell subues the Scots |
| 1650s | Scots transported to Americas by Cromwell |
| 1651 | Battle of Worcester |
| 1670s | Scots transported to Americas by Charles II |
| 1672 | Over six thousand Irish women and children sold as slaves since English rule began |
| 1684 | First Scotch-Irish emigrants to America |
| 1689 | Battle of Dunkeld – English defeated by Highlanders |
| 1690s | Movement of Scots to Ireland due to adverse economic conditions |
| 1690s | Scots emigrated to New World as religious refugees |
| 1700 | Mass emigration to America begins |
| 1708 | The Act of Union |
| 1708–90 | Scottish emigration – principally Lowlanders |
| 1715 | First Jacobite Rebellion |
| 1715 | Battle of Preston – defeat of James II |
| 1715–16 | Pardoned Jacobite rebels retreat to Carolina |
| 1716–17 | Crop failures in Ireland cause Ulster Scots to emigrate to Massachusetts and New Hampshire
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| 1718–75 | Convicts forcibly transported to New World |
| 1720–50s | Emigration of small farmers and craftsmen from Ulster |
| 1740s | Western Isles families emigrate to Americas |
| 1745 | Second Jacobite Rebellion |
| 1746 | Battle of Culloden and defeat of Prince Charles Edward Stuart – surviving Highlanders sent to Caribbean as slaves |
| 1747 | Act of Proscription bans wearing of tartan, teaching of Gaelic language and gathering of Highlanders
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| 1759 | Battle of Quebec |
| 1762 | Clearances begin – Sir John Lockhart-Ross brings sheep to his Balnagowan estate, installs fences and Lowlander shepherds |
| 1763–75 | Highland Clearances and subsequent emigration |
| 1776 | Declaration of Independence |
| 1777 | Battle of Charleston, Virginia |
| 1782 | Act of Proscription repealed |
| 1783 | Independent United States of America |
| 1828–60 | Scottish depopulation, resulting in emigration from Scotttish lowlands |
| 1834 | Poor-law Amendment Act |
| 1836–37 | Scottish potato famine |
| 1846–51 | Irish Famine emigration |
| 1847–54 | 'Celtic' emigration from Ireland and Scottish Highlands |
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